Showing posts with label Medical Research. Show all posts
Showing posts with label Medical Research. Show all posts

Monday

2,000 iPhones given for free by Japanese gov’t to passengers stuck on ship due to coronavirus


The Japanese government gave away 2,000 free iPhones to passengers stranded on a cruise ship due to the COVID-19 outbreak, caused by the novel coronavirus. The country’s health minister stated that 355 people onboard the ship have tested positive for the virus.

The smartphones were handed to each cabin so passengers could access an app made by the government, as per Macotakara via 9to5mac last Friday, Feb.14.

The said app from the Japanese Ministry of Health, Labour and Welfare will allow people on the quarantined ship to consult with a doctor. Smartphones registered outside of Japan are unable to access the app. This also prompted the ministry to hand out the devices to the passengers.

According to the report, the 2,000 devices were handed out to ensure that each cabin had one unit.

The ship arrived near the Japanese coast earlier this month with more than 3,700 people on board from over 50 countries. It was placed under quarantine after a passenger who left the vessel in Hong Kong tested positive for the virus.

The Japanese government may begin testing the travelers for the disease from Feb. 18, the captain said. Passengers with negative results will be allowed to disembark the ship starting Feb. 21.


The disease has already killed over 1,000 people and infected more than 42,000 worldwide. The World Health Organization named it COVID-19 after declaring the outbreak as a global health emergency. Ryan Arcadio/JB


source: technology.inquirer.net

Thursday

Elderly exercisers have fewer broken bones after falls


NEW YORK - Older adults who exercise are less likely to fall, but if they do, they're also less likely to get hurt, a new analysis suggests.

Researchers found that older adults taking part in fall prevention exercise programs were about 37 percent less likely to be injured during a tumble, compared to non-exercising participants.

"Falls are recognized as a serious and common medical problem experienced by older adults, but it's also widely known that falls are preventable, and that exercise is an efficient way to prevent them," Fabienne El-Khoury, the study's lead author, told Reuters Health in an email.

"However there was no clear evidence that exercise (programs) can also reduce severe or more moderate injuries caused by falls, even though injuries due to falls have serious medical, psychological and economic consequences," El-Khoury added.

She is a doctoral candidate at the University of Paris-Sud and at INSERM, the French National Institute of Health and Medical Research.

Between 30 to 40 percent of people age 65 or older fall at least once each year, according to the government-backed US Preventive Services Task Force (USPSTF). About five to 10 percent of those people will have a serious injury such as a hip fracture.

For older adults who live independently and are at a high risk for falls, the USPSTF recommends exercise or physical therapy and/or vitamin D supplements.

Older people who are at a high risk for falls include those with a history of falls, mobility problems and those who have trouble getting up from a chair and walking.

While several studies have found that exercise programs reduce tumbles, the researchers wondered whether those programs also prevented injuries if older adults did fall.

For the analysis, published in BMJ, El-Khoury and her colleagues used data from 17 previous studies comparing 2,195 people assigned to take part in exercise programs and 2,110 people who were not.

The average age of the people included in the analysis was about 77 years old and more than three quarters of the participants were women.

Overall, the researchers found that people in the exercise group were about 37 percent less likely to be injured during a fall, compared to the non-exercisers. Those injuries could be anything from bruises to broken bones.

The exercisers were 61 percent less likely to have broken bones after falls, and 43 percent less likely to experience a fall leading to any injury serious enough to warrant admission to a hospital.

El-Khoury said it's hard to know how many injuries those reduced risks represent, because all of the studies reported injuries differently. Also, results varied between studies.

For example, there were 81 injuries per 100 people over a year in the exercise group of one study included in the analysis. There were 134 injuries per 100 people over a year for the non-exercise group.

In other studies, researchers have found no such difference between groups based on exercise.

When there is a difference, Yvonne Michael, who has studied falls among older people but wasn't involved in the new analysis, said the reason could be that the bodies of people who exercise are better at absorbing a fall.

The authors suggest the minds of people who exercise may also be sharper than those of non-exercisers and they can respond better to falling, for instance by grabbing onto something.

Michael said the findings are consistent with previous studies, but there is still uncertainty about which exercise programs work best.

In the new analysis the programs emphasized exercises to improve balance, but most had several components. Three of the included studies used Tai Chi.

It's also uncertain whether routine activities, such as gardening, walking and mowing the lawn, are just as good as more structured exercise programs.

"It's harder to test the routine activity because it doesn't fit well into a randomized controlled trial setting," said Michael, an associate professor at the Drexel University School of Public Health in Philadelphia.

She added, however, that people living in urban or suburban areas should be able to find structured exercise programs through their local senior center. Also, some medical plans include exercise programs for older adults.

Those are typically low cost and may even be included in some insurance plans, she said.
"I think the evidence continues to grow in terms of the benefit of physical activity," Michael said. "It seems like there's really no downside to staying active." —Reuters

source: gmanetwork.com

Want to know if you have Alzheimer's? Try some peanut butter


A-la peanut butter sandwiches! Just as The Amazing Mumford invokes peanut butter for his magic tricks, researchers at the University of Florida are now turning to the treat for detecting Alzheimer’s disease in its early stages.

Graduate student Jennifer Stamps thought of using peanut butter to test patients for their sense of smell, which could deteriorate with cognitive decline.

"One of the first places in the brain to degenerate in people with Alzheimer’s disease is the front part of the temporal lobe that evolved from the smell system, and this portion of the brain is involved in forming new memories," the university said in a news release.




Stamps and Dr. Kenneth Heilman, the James E. Rooks distinguished professor of neurology and health psychology in the UF College of Medicine’s department of neurology, said this test could be used by clinics that cannot run more elaborate tests.

The university added the peanut butter test will be one more added tool in an arsenal of clinical tests for neurological function in patients with memory disorders.

“We see people with all kinds of memory disorders. This can become an important part of the evaluation process,” Heilman said.

With her colleagues, Stamps, a graduate student in the UF McKnight Brain Institute Center for Smell and Taste, decided to test sensitivity with peanut butter and a ruler.

They reported the findings of a small pilot study in the Journal of the Neurological Sciences.

Stamps said she thought of peanut butter because it is a “pure odorant” that is only detected by the olfactory nerve and is easy to access.

Study details

In the study, patients who were coming to the clinic for testing sat down with a clinician with a tablespoon (14 grams) of peanut butter and a ruler.

The patient would close his or her eyes and mouth and block one nostril. The clinician then opened the peanut butter container and held the ruler next to the open nostril as the patient breathed.

The clinician would move the peanut butter up the ruler one centimeter at a time until the patient could detect an odor.

After recording the distance, the clinician would repeat the procedure on the other nostril after a 90-second delay.

In the study, the researchers found patients in the early stages of Alzheimer’s disease had a dramatic difference in detecting odor between the left and right nostril.

The left nostril turned out to be impaired and did not detect the smell until it was about 10 cm closer to the nose than the right nostril.

Patients with other kinds of dementia did not have such a degraded sense of smell, the university noted.

More studies needed

The researchers said more studies may be needed, after noting that of the 24 patients tested who had mild cognitive impairment, 10 showed a left nostril impairment and 14 patients did not.

“At the moment, we can use this test to confirm diagnosis. But we plan to study patients with mild cognitive impairment to see if this test might be used to predict which patients are going to get Alzheimer’s disease,” Stamps said. — TJD, GMA News

source: gmanetwork.com

Monday

Stem cell advance boosts prospects for retina treatment


PARIS - Blind mice have been able to see once more in a laboratory exploit that marks a further boost for the fast-moving field of retinal therapy, according to a study published on Sunday.

Scientists in Britain used stem cells—early-stage, highly versatile cells—taken from mice embryos, and cultured them in a lab dish so that they differentiated into immature photoreceptors, the light-catching cells in the retina.

Around 200,000 of these cells were then injected into the mice's retinas, some of which integrated smoothly with local cells to restore sight.

The rodents were put through their paces in a water maze and examined by optometry to confirm that they responded to light.

Embryonic stem cells "could in future provide a potentially unlimited supply of health photoreceptors for retinal transplantations to treat blindness in humans," Britain's Medical Research Council (MRC) said in a press release.

Photoreceptor loss lies behind degenerative eye diseases such as retinitis pigmentosa and age-related macular degeneration, also called AMD.

Stem cells have triggered a huge interest and investment on the back of hopes that they can become replacement tissue, grown in a lab dish, for cells damaged by disease or accident.

But the exciting field has to overcome big obstacles.

One is the ability to coax these immature cells into safely becoming the specialised cells that are needed, rather than turn cancerous.

This is where the new work marks a gain, according to lead researcher Robin Ali at the University College London Institute of Ophthalmology and Moorfields Eye Hospital.

His team previously found that sight could be restored in blind mice by transplanting immature photoreceptors called rod cells that were taken from the retinas of healthy rodents.

The latest research takes things further because the transplanted material comprises all the different nerve cells needed for sight—and they were not taken from other animals.

Instead, they were grown in a lab and differentiated into the right cells thanks to a new technique, pioneered in Japan, that replicates the shape of the retina.

"Over recent years, scientists have become pretty good at working with stem cells and coaxing them to develop into different types of adult cells and tissues," said Ali.

"But until recently, the complex structure of the retina has proved difficult to reproduce in the lab. This is probably because the type of cell culture we were using was not able to recreate the developmental process that would happen in a normal embryo."

Ali added: "The next step will be to refine this technique using human cells to enable us to start clinical trials."

The study appears in the journal Nature Biotechnology.

Last month, Japanese authorities approved proposals for the world's first clinical trials using stem cells harvested from a patient's own body.

The goal is to test therapy for AMD using so-called induced pluripotent stem cells, or iPS.

These are adult cells that have been reprogrammed to return to their infant, versatile state. Provided that they are proven safe, they can provide a non-controversial alternative to stem cells culled from early-stage embryos. —Agence France-Presse

source: gmanetwork.com